RiteMED Omeprazole Dosage/Direction for Use

Injection: Patients who are unable to take oral medication, e.g. in severely ill patients with either reflux oesophagitis, duodenal ulcer or gastric ulcer: Omeprazole 40 mg, can be given as IV bolus or infusion once daily for up to 5 days.
Zollinger-Ellison syndrome: Initially 60 mg IV daily, then adjust dose individually. For doses exceeding 60 mg daily, given as divided doses twice daily.
Administration: Administration by intravenous route only and not by any other route.
Use in Children: The safety and effectiveness of omeprazole sodium injection in children is not established.
Use in Elderly Patients: It is not necessary to adjust the dose of omeprazole in elderly patients.
However, a slight decrease in elimination rate and an increase in bioavailability are likely to occur in such patients.
Use in Patients with Impaired Liver Function: Bioavailability and half-life of Omeprazole can increase in patients with hepatic impairment. UK licensed product information recommends that a maximum daily oral dose of 20 mg be used in these patients; a daily intravenous dose of 10 to 20 mg is considered sufficient.